Stadium: Fred G. Hughes Stadium Round: 1
| NCAAF | 2022/09/10 23:00 | Northeastern State Riverhawks v Missouri Southern Lions | W | 13-30 |
| NCAAF | 2021/09/11 19:00 | Missouri Southern Lions v Northeastern State Riverhawks | L | 17-21 |
| NCAAF | 2019/10/26 19:00 | Northeastern State Riverhawks v Missouri Southern Lions | W | 7-86 |
| NCAAF | 2018/10/20 22:00 | Missouri Southern Lions v Northeastern State Riverhawks | W | 24-19 |