Stadium: Knapp Center
Home Manager: Darian DeVries Away Manager: Drew Valentine
| NCAAB | 2021/03/07 19:00 | Drake v Loyola Chicago | W | 65-75 |
| NCAAB | 2021/02/14 20:00 | Loyola Chicago v Drake | L | 50-51 |
| NCAAB | 2021/02/13 17:00 | Loyola Chicago v Drake | W | 81-54 |
| NCAAB | 2020/02/26 01:00 | Drake v Loyola Chicago | W | 60-64 |
| NCAAB | 2020/01/08 02:00 | Loyola Chicago v Drake | L | 62-65 |
| NCAAB | 2019/02/06 00:00 | Drake v Loyola Chicago | W | 64-86 |
| NCAAB | 2019/01/05 20:00 | Loyola Chicago v Drake | W | 85-74 |
| NCAAB | 2018/02/08 01:00 | Drake v Loyola Chicago | W | 57-72 |
| NCAAB | 2022/01/28 01:00 | Loyola Chicago v Southern Illinois | W | 44-39 |
| NCAAB | 2022/01/26 01:00 | Southern Illinois v Loyola Chicago | W | 47-59 |
| NCAAB | 2022/01/22 20:30 | Missouri State v Loyola Chicago | L | 79-69 |
| NCAAB | 2022/01/19 01:00 | Loyola Chicago v Evansville | W | 77-48 |
| NCAAB | 2022/01/16 01:00 | Loyola Chicago v Indiana State | W | 64-56 |
| NCAAB | 2022/01/12 02:00 | Valparaiso v Loyola Chicago | W | 74-81 |
| NCAAB | 2022/01/08 21:00 | Bradley v Loyola Chicago | W | 71-78 |
| NCAAB | 2022/01/06 19:00 | San Francisco v Loyola Chicago | W | 74-79 |
| NCAAB | 2022/01/27 01:00 | Drake v Illinois St | W | 89-88 |
| NCAAB | 2022/01/22 23:00 | Drake v Northern Iowa | W | 82-74 |
| NCAAB | 2022/01/20 01:00 | Bradley v Drake | L | 83-71 |
| NCAAB | 2022/01/18 01:00 | Drake v Southern Illinois | W | 60-59 |
| NCAAB | 2022/01/13 01:00 | Illinois St v Drake | W | 75-86 |
| NCAAB | 2022/01/08 22:00 | Drake v Evansville | W | 60-59 |
| NCAAB | 2022/01/03 01:00 | Drake v Missouri State | L | 56-61 |
| NCAAB | 2021/12/29 01:00 | Drake v Mount Marty | W | 82-53 |