Stadium: Five Star Stadium Round: 1
Home Manager: Drew Cronic Away Manager: Rusty Wright
| NCAAF | 2021/03/27 16:00 | Mercer v Tennessee Chattanooga | L | 35-28 |
| NCAAF | 2019/10/05 20:00 | Tennessee Chattanooga v Mercer | W | 34-17 |
| NCAAF FCS | 2018/11/10 18:00 | Mercer v Tennessee Chattanooga | L | 13-9 |
| NCAAF | 2017/10/14 19:30 | Mercer v Tennessee Chattanooga | L | 30-10 |
| NCAAF | 2021/11/06 17:30 | Tennessee Chattanooga v Wofford | W | 35-10 |
| NCAAF | 2021/10/30 17:30 | Furman v Tennessee Chattanooga | W | 3-13 |
| NCAAF | 2021/10/23 17:00 | Tennessee Chattanooga v Samford | W | 55-13 |
| NCAAF | 2021/10/16 17:30 | East Tennessee State v Tennessee Chattanooga | W | 16-21 |
| NCAAF | 2021/10/09 17:30 | Tennessee Chattanooga v VMI | L | 34-37 |
| NCAAF | 2021/10/02 17:30 | Western Carolina v Tennessee Chattanooga | W | 17-45 |
| NCAAF | 2021/09/18 16:00 | Tennessee Chattanooga v Kentucky | L | 23-28 |
| NCAAF | 2021/09/11 23:00 | Tennessee Chattanooga v North Alabama | W | 20-0 |
| NCAAF | 2021/10/30 18:00 | Mercer v The Citadel | W | 34-7 |
| NCAAF | 2021/10/23 22:00 | Wofford v Mercer | W | 14-45 |
| NCAAF | 2021/10/16 20:00 | VMI v Mercer | L | 45-7 |
| NCAAF | 2021/10/09 19:30 | Mercer v Western Carolina | W | 34-24 |
| NCAAF | 2021/10/02 22:00 | Samford v Mercer | W | 42-45 |
| NCAAF | 2021/09/25 18:00 | Mercer v Furman | W | 24-3 |
| NCAAF | 2021/09/11 20:00 | Mercer v Alabama | L | 14-48 |
| NCAAF | 2021/09/02 23:00 | Mercer v Point University Skyhawks | W | 69-0 |